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In 2019, the Canadian Society of Allergy and Clinical Immunology (CSACI) released a similar statement, stating that diphenhydramine, along with other first-generation antihistamines, should be used only as a last resort, with eventual consideration given to having them only available behind the counter in pharmacies. David Fischer, M.D., who is a senior author of the CSACI statement and an allergist at Western University in Canada, goes so far as to say that all allergists hate this drug. Several European countries, including Germany, the Netherlands, and Sweden, have already restricted access to diphenhydramine to prescription-only use

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At ThinWorks, CJC-1295 is paired with Ipamorelin, a growth hormone secretagogue that works through a different receptor family, so the two signals complement each other