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Substituting the C-tail region of GLP-1R with that of GIPR had no effect on either total expression or cell surface expression, whereas the reciprocal substitution impaired GIPRs cell surface expression (Supplementary Figure 1D
GIP Receptor Antagonists in the Pharmacotherapy of Obesity: Physiologic, Genetic, and Clinical Rationale
I went right in the middle with 12.5 mg, but need blood work to evaluate efficacy
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