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The peptide contains an intramolecular disulfide bridge between two cysteine residues, which constrains its three-dimensional structure

S (Study design): Randomised controlled trials (RCTs), non-randomised controlled trials (N-RCTs), cohort studies, and case-control studies

LPS-free indicates that the AOD9604 peptide has been manufactured to minimize lipopolysaccharide contamination, which can otherwise interfere with metabolic or inflammatory research data