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Green et al 26 Severe clinical abnormalities should be treated intensively with B 12 , cyanoB 12 or hydroxyB 12 : HydroxyB 12 is commonly used in Europe, often at intervals of 23 months, as it seems to have better retention than cyanoB 12
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Excessive alcohol and drug use diminishes the amount of NAD naturally found in the body
These doses were used within a controlled research environment with rigorous safety monitoring they do not represent guidance for use outside of trials
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