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Obesity is a network disease involving appetite regulation, reward signaling, gut-brain hormones, and energy expenditure pathways
However, acetazolamide is poorly tolerated in patients while GLP-1RAs are typically better tolerated, with only transient nausea as the predominant adverse effect [105]
Our future steps include incorporating these devices with microfluidics for improved sample handling and translation to other laboratories and clinics
Schedule: One subcutaneous injection a week across an 816 week course, with the dose raised in phases
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