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In this context, it has been shown in animal models that recombinant human TRX-1 (rhTRX-1) provides cytoprotection by reducing ROS formation
This treatment promotes functional recovery in rats following complete spinal cord transection, significantly upregulating the expression of GPX4 and FTH1, while downregulating ACSL4 and COX2 expression, suggesting its potential to modulate anti-ferroptosis pathways involved in SCI recovery (Wang J
ISBN 978-1-60761-755-6
Although challenges remain, with the advancement of precision medicine concepts and the development of novel drugs, MR is highly likely to become an important precision weapon in the comprehensive cancer treatment toolbox in the coming years, particularly offering new hope for patients carrying specific metabolic defects (such as MTAP deletion)
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