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Kooij IA, Sahami S, Meijer SL, et al

The improvement in the TyG index and to a lesser extend the HOMA-IR is to be expected as the FPG levels improved significantly following linagliptin intervention in the high GLP-1 group of both the prediabetes and T2D populations despite the non-significant drop in the fasting insulin levels

When to Consult Your Healthcare Provider If you are thinking about using one of these options, get an appointment with your healthcare provider and consult about your treatment options before finally choosing between these drugs, Ozempic and compounded semaglutide