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TP53 mutations in functional corticotroph tumors are linked to invasion and worse clinical outcome

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However, provided variations in the water content within the sample are much smaller than the variations in the metabolite levels, variance shared between normalized metabolite signals can be assumed to arise largely from shared variance in metabolite concentrations [52]

100mcg = 0.02mL = 2 units 250mcg = 0.05mL = 5 units The second concentration requires smaller volumes but makes precise measurement more difficult