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Although -cell numbers and mass increase about 1.42.4 times relative to normal (43) during mid-pregnancy lactogenic surge, in patients with gestational diabetes mellitus (GDM), insulin requirements often increase during the third trimester that coincides with the increase in insulin resistance to maintain good glycemic control

Renal Protective Effects Emerging evidence suggests Semaglutide may have nephroprotective effects, slowing the progression of diabetic kidney disease

Medical interventions should be deployed in tandem with policy decisions that address the environmental drivers of obesity and type 2 diabetes

Furthermore, Novo Nordisk is preparing for the expiration of its key semaglutide patent in China in 2026, potentially opening the door to lower-cost generics in most important markets