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Cardiovascular disease - the leading global cause of death Nonetheless, use of semaglutide could help address CVD, which remains the leading cause of mortality around the world, and obesity, which is still an epidemic, Cynthia Jackevicius of Western University of Health Sciences emphasised the potential population impact of semaglutide, stating that it could have a profound effect on reducing morbidity and mortality from cardiovascular disease

1 Introduction Heart failure (HF) and cognitive impairment are two common health conditions that often coexist in the general population (Virani et al., 2021)

Interestingly, the strong dependence of mitochondrial -oxidation on autophagic and fatty acid (FA) catabolic processes makes some tumors more resistant to nutrient deprivation and environmental stressors 13

The titration protocol exists because GLP-1 receptor agonists cause gastrointestinal side effects, primarily nausea, that are dose-dependent