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Most importantly, improvement in glucose control and weight reduction are obtained without increasing the overall risk of hypoglycemia and the number of severe hypoglycemic events
Elevation of intracellular Ca 2+ activates scramblase to ensure PS externalization, opens the Gardos channels, resulting in K + efflux and subsequent cell shrinkage, and mobilizes calpain, leading to cytoskeleton degradation and membrane microvesiculation [78]
Medication on its own is not a magic fix
Therefore, continuous testing and calibration are essential to ensure accuracy in aPTT results
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