Firstly, some people believe that cerebral insulin resistance in patients with AD may not be insulin resistance in the true sense of the word but may instead arise from dysfunctional insulin transport across the BBB and that this transport defect may be caused by abnormal BBB function indirectly resulting from peripheral insulin resistance (Qian et al., 2024)
Rubino, F.M
The right treatment depends on medical history, safety, FDA approval status, access, tolerance, side effects, muscle-preservation needs, metabolic risk, and long-term planning
It is essential to verify the patients understanding of the prescribed therapeutic regimen, clarify the benefits that can result from the therapy, discuss possible adverse events, and provide useful advice to minimize them, as well as simplify the therapeutic regimen when appropriate [73]