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So, for those pondering, "can I drink coffee while taking Tirzepatide?", we'd suggest careful timing of coffee intake, especially if sleep quality is a concern

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However, temporary lower dosing during titration is safe and often reduces early nausea and GI side effects, improving your ability to tolerate and continue treatment long-term

The trial enrolled 13,165 patients with type 2 diabetes and pre-existing cardiovascular disease from May 29, 2020, to June 27, 2022, with analysis carried out from July 2025 to February 2026