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Secondary mitochondrial dysfunction Acquired dysfunction may develop from oxidative stress, inflammation, nutrient deficiency, medication toxicity, toxic exposure, aging, metabolic disease, infection, poor sleep, inactivity or chronic illness
ECG, physical exam, neurological assessments, and markers (NfL, p-tau 181, GFAP, hs-CRP) at week 52, 104, 156
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its not a direct measure of body fat
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