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Modern incretin-based therapy still relies heavily on appetite suppression, but the addition of glucagon receptor activation may shift the model toward a broader metabolic strategy: reducing food intake while increasing energy expenditure and improving hepatic lipid metabolism
Daytime (6:0024:00 h) and nighttime (24:006:00 h) outcomes were also assessed
NAC uniquely impacted pathways such as gluconeogenesis, mitochondrial electron transport chain, branched-chain fatty acid oxidation, phytanic acid peroxisomal oxidation, and glycine-serine metabolism
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