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Discard remainder of vial 28 days after first puncture

The sprays contain substances such as melanotan 2 a synthetic hormone not approved for use in the UK which can cause nausea, vomiting, high blood pressure, kidney problems, and an increased risk of melanoma skin cancer

To evaluate the therapeutic potential of PCSK5 following MI, adenovirus-associated virus 9 (AAV) vectors were employed to overexpress the Pcsk5 gene in the hearts of 68 week-old male mice, with a control group receiving AAV-Ctrl, followed by MI surgery (Fig