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Results showed that among people without diabetes, GLP-1 drug use rose from 0.1% of the population in 2018 to 0.4% in 2022
For example, selonsertib (GS-4997) is a highly selective and potent ASK1 inhibitor with potential anti-inflammatory, anti-tumour, and anti-fibrotic activities 40
Some compounded tirzepatide formulations even include B12but these are not FDA-regulated and carry potential risks
Wegovy, a semaglutide formulation approved for weight loss, is included in just 1% of Marketplace plan formularies, while Ozempic, which has the same active ingredient but is approved for diabetes treatment and sometimes used off-label for weight loss, is included in 82% of Marketplace plan formularies
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