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In this phase 2 study, 48 patients with obesity or who were overweight and also had alcohol use disorder were randomly assigned either a placebo or a low dose of semaglutide, with researchers testing how much the drug changed drinking habits after about two months
For higher doses (1.0 mg and above), the 10mg vial is more cost-effective because you use more of the vial contents within the 28-day window
Regarding gene expression, MASLD and MASH patients displayed elevated hepatic mRNA levels of GSTA1 as compared to a healthy group (Lee et al
Switching back prematurely means you will never know whether higher semaglutide doses would have worked
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