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At a cellular level, both the pill and the injection utilize the same active molecule (semaglutide) to mimic your bodys natural hormone (GLP-1), which slows gastric emptying to increase fullness, stimulates insulin release to manage blood sugar, and acts on the brain to reduce hunger and cravings

Indeed, the combined use of these medications is suggested to be synergistic and, as reported in a recent meta-analysis, superior outcomes with the addition of a GLP-1 RA to SGLT2i can be observed in type 2 diabetes, although observations of cardiovascular and mortality outcomes are limited [29]

You have complications including ruptures in the colon wall, fistulas, or other serious tissue damage

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