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In the multicenter STEP trial with patients with overweight or obesity and heart failure with preserved ejection fraction (STEP-HFpEF), patients treated with semaglutide 2.4 mg had mean percentage reduction in body weight of 13.3% and experienced significant improvements in heart failure-related symptoms, walking distance, and blood pressure measurements from baseline to 52 weeks [15]
They are complementary, not competitors
Key Takeaways Wegovy pill and injection are both FDA-approved for weight management, but they differ in dosing schedules, absorption, and instructions
Physician-managed GLP-1 therapies work biologically to regulate appetite, improve insulin sensitivity,and target stubborn fat helping you achieve sustainable, optimized weight
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