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[12] [13] The medication is indicated for adults with type 2 diabetes as an adjunct to diet and exercise, and for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbid condition
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Clinical trial data demonstrate that initiating directly at 5 mg or higher produces a substantially higher rate of nausea, vomiting, and early discontinuation
Animal studies and clinical trials suggest that L-carnitine can improve nitrogen balance under pathological stress by enhancing protein synthesis, reducing protein breakdown, inhibiting apoptosis, and mitigating inflammatory responses (74)
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