semaglutide cause muscle loss Did You Know Ozempic (semaglutide) causes significant weight that includes not only fat but also lean mass, with some studies showing up to 39% of lost weight being muscle, leading Does Semaglutide Cause Lean Muscle

The digestive changes caused by GLP-1 medications may also affect how efficiently the body processes certain foods, which could contribute to the development of sulphur-smelling burps in some patients

Nonetheless, there is still some controversy on the in vivo involvement of FFAR2 and FFAR3 in GLP-1 modulation (301, 302), with some reports indicating that blockade of GPR43 in vitro releases GLP-1 (303) and others indicating different mechanisms of action, with FFAR2 releasing PYY from intestinal L-cells (81), while FFAR3 restricted to submucosal neuronal activity (295) despite its apparent expression by the majority of enteroendocrine cells (83)

Not everyone who takes a GLP-1 is focused on weight, and changes in sexual wellbeing are not tied to a specific body size

doi: 10.1164/rccm.201910-1911tr 10