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Abstract COVID-19 pandemic is posing an unprecedented sanitary threat: antiviral and host-directed medications to treat the disease are urgently needed
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They are typically released from damaged or dying cells and activate the innate immune system by interacting with pattern recognition receptors (PRRs), including Toll-like receptors (TLRs) and NLRPs (Nucleotide-binding oligomerization domain, Leucine rich Repeat and Pyrin domain containing, also known as NOD-like receptors)
2011 Sep;17(9):82733
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