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no Phase II or III trials published Most common AOD-9604 side effect / Injection-site reaction (redness, swelling) Most common reported MOTS-c side effect / Transient flushing and mild GI discomfort (anecdotal, not trial-confirmed) Growth hormone axis impact / AOD-9604 does not activate the GH receptor
Semaglutide depends on an individuals preference
Impaired Bile Flow Cholestasis, gallstones or reduced bile delivery can interfere with fat digestion and the biliary elimination of selected compounds
It is important to emphasize that these findings are derived exclusively from experimental and animal research, and comprehensive clinical studies are required to evaluate safety, effectiveness, and potential relevance in human cardiovascular conditions
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