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Patients should always follow the specific advice of their bariatric team, as individual requirements vary

Ideal candidates for leading with NAD+: Patients over 40 experiencing persistent fatigue that does not resolve with sleep or lifestyle changes Individuals with metabolic syndrome, insulin resistance, or difficulty managing weight despite dietary effort Patients recovering from substance use, where NAD+ IV therapy has shown measurable benefit in reducing withdrawal symptoms and cravings High-performance athletes or executives seeking cognitive edge and faster physical recovery Patients with early neurodegenerative concerns who want evidence-supported mitochondrial support GHK-Cu Dosage and NAD+ Dosage: What Clinical Protocols Actually Use Dosing varies based on delivery route, patient body weight, and clinical goal

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By synthesizing current research advancements, the present review aims to provide new perspectives on the common pathological pathways underlying these diseases and to establish a theoretical foundation to guide the development of effective clinical interventions