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Safety and efficacy of once-weekly efruxifermin versus placebo in metabolic dysfunction-associated steatohepatitis (HARMONY): 96-week results from a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial

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For example: According to an October 2024 study in the journal Scientific Reports, GLP-1 receptor agonists (a category that includes semaglutide, which is the primary active ingredient in Ozempic) are associated with elevated risk of psychiatric consequences particularly in the domains of depression, anxiety, and suicidal outcomes. A June 2024 report in the journal Innovations in Clinical Neuroscience reported that additional data is required to ascertain semaglutides effect on mood