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Researchers have also found that certain factors can trigger the onset of vitiligo and perpetuate the condition, including: Chronic stress: Stress can seriously affect your immune system, potentially triggering or worsening vitiligo symptoms
Additionally, patients in the bevacizumab arm also showed an enhanced objective response rate (78.5% versus 57.4%) and duration of response (10.4 months versus 7.4 months) compared with those of patients in the placebo arm
The case of NAC encapsulates the core challenges of MIRI therapy: while its mechanism of enhancing endogenous defenses is conceptually superior to direct scavenging (as argued in Section 2.3), its clinical potential is ultimately nullified by the formidable practical hurdles of delivery and timing required to counteract the rapid and localized oxidative burst (Section 2.1)
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