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Bulletin of Experimental Biology and Medicine, 2003
Muscle loss remains underappreciated: 25-39% of weight lost on GLP-1 medications is lean mass
To test this, we inhibited the cysteine/glutamate antiporter System Xc - using Imidazole Ketone Erastin (IKE), thereby limiting substrate availability for GSH synthesis ( Figure 6H )
Greenway FL, Fujioka K, Plodkowski RA, Mudaliar S, Guttadauria M, Erickson J, et al
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