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Women with a history of depression, anxiety, or mental health challenges should ensure their prescribing doctor is aware of this ongoing investigation and that their mental health is being monitored throughout treatment

HCS catalyses the transfer of biotin to 4 biotin-dependent enzymes: 3-methylcrotonyl CoA carboxylase, propionyl CoA carboxylase, pyruvate carboxylase, and acetyl CoA carboxylase