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Methionine has a half-life of approximately 2.5 days, making weekly dosing intervals sufficient to maintain therapeutic lipotropic activity without accumulation
La presencia de algunos factores concomitantes puede potenciar el efecto txico de la Bb: acidosis, hipoxia, convulsiones, edad gestacional y postnatal, velocidad de incremento srico de Bb, concentracin srica de albmina - Encefalopata bilirrubnica aguda: 1) fase precoz, con hipotona, letargia y mala succin
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