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In rare cases, particularly with severe megaloblastic anaemia, rapid correction of B12 deficiency can affect potassium distribution in the body

The United Kingdom National Quality Assessment Scheme for Haematinic Assays warns against false B12 results and the risk of neurological damage: In the event of any discordance between clinical findings of B12 deficiency and a normal B12 laboratory result, then treatment should not be delayed

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When cessation is advised, timeframes often consider the medication's dosing frequency, though specific recommendations vary between hospitals and clinicians