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Unopened semaglutide pens should typically be stored in the refrigerator between 36F and 46F to preserve effectiveness
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Standard protocols start at 0.25mg weekly for the first four weeks, titrating up to 0.5mg, then 1.0mg, and potentially 1.7mg or 2.4mg depending on response and tolerance
Recent clinical trials and meta-analyses from 2022 to 2025 show significant results validating the efficacy and safety of this medication for weight loss
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