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The compound binds the growth-hormone-releasing-hormone receptor on somatotrophs, mimicking endogenous GHRH and triggering an adenylyl-cyclase / cAMP / protein-kinase-A signalling cascade
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However, unlike ghrelin itself, Ipamorelin does not significantly affect hunger or gastric motility, which makes it an ideal peptide for studies that require GH release without secondary metabolic effects
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