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The total number of GLP-1 users is expected to increase significantly over the coming years as pharma expands production capacity, reduces prices, develops new products with fewer side effects, and offers more user-friendly dosage forms

Stopping use only protects against scheduled events, not surprise testing

The least-squares mean percentage change in body weight from baseline was -7.2% in the 1 mg group, -12.9% in the 4 mg group (starting at 2 mg), -17.1% in the combined 4 mg groups, -17.5% in the combined 8 mg groups, and -17.5% in the 12 mg group, compared with -1.6% in the placebo group

These effects are often manageable, but they can become frustrating if treatment moves faster than the body can tolerate