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These findings underscore the developmental importance of early microbial signals in shaping neural circuits and behavior, processes modulated by molecules such as reelin, which controls dendritic growth and synaptic receptor function in post-natal entorhinal cortex neurons (Hamad et al., 2021b,a, 2024b,a
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BPC 157 enhanced the phosphorylation of Src, Cav-1 and eNOS which was abolished by pretreatment with Src inhibitor, confirming the upstream role of Src in this signal pathway
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