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The FDA's Center for Drug Evaluation and Research has been reviewing bulk drug substances eligible for use in compounding under sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act [10]

GLP-1 receptor agonists mimic the action of naturally occurring hormones that regulate blood glucose and appetite by: Slowing gastric emptying, promoting feelings of fullness Reducing appetite signals in the brains hunger centers Improving insulin secretion while suppressing glucagon release Creating a caloric deficit through reduced food intake Originally developed for type 2 diabetes management, these medications have gained FDA approval for chronic weight management in adults with obesity or overweight with weight-related comorbidities

43: 75965 Higashi N, Kume A, Tanogushi T, et al

Front Microbiol 13:933550