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Pharmacovigilance data show elevated reporting-odds ratios for dry mouth across the entire medication class, with semaglutide at 1.34 and tirzepatide at 1.35
In ATTAIN-1, adverse event-related discontinuation rates were 5.3% with orforglipron 6 mg, 7.6% with 12 mg, and 10.3% with 36 mg, compared with 2.7% with placebo
This powerful treatment, administered weekly, offers a holistic approach to weight loss by curbing appetite, increasing feelings of fullness, and boosting energy levels
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