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Human thyroid tissue expresses GLP-1 receptors at much lower levels than rodent tissue, with expression not exceeding 30% of human thyrocytes and parafollicular C-cells
It is the target for several FDA-approved antidiabetic medications called incretin mimetics: These incretin mimetics are glucagon-like peptide 1 (GLP-1) analogs that mimic the physiological action of GLP-1 and thereby potentiates the incretin effect in type 2 diabetic patients
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