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I am not a medically trained person but I've had Pernicious Anaemia (one of many causes of B12 deficiency) for more than 46 years
SNAP-GLP1R:CHO-K1 cells were incubated with LUXendin492 (LUX492), LUXendin551 (LUX551), and LUXendin615 (LUX615) before orthogonal SNAP-labeling with either cell-impermeable SBG-TMR or SBG-SiR and confocal imaging (nuclei were stained using Hoechst33342) (scale bar = 10 m) (n = three images from experiments performed in duplicate)
A search of Genbank and EST databases revealed four unique sequences that encode glutathione synthetases
The biological scissors cut glutathione into its constituent amino acidscysteine, glutamic acid, and glycinemaking it useless as a whole antioxidant
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