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Although multiple PDE isoforms are expressed in the central nervous system (Table 1), only a limited number of isoforms demonstrate a mechanistic alignment with the neurochemical pathways, particularly D 1 /D 2 , central to schizophrenia pathophysiology (Lusardi et al., 2024)
Variations in product color may occur
Concern and Recommendations: Medically, the major concern right now with BPC 157 is a lack of evidence confirming safety in humans
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