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Several indirect mechanisms may explain why some patients report muscle pain or weakness while taking GLP-1 medications, even in the absence of direct myotoxicity

A pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM trials examined 1,461 patients with HFpEF, most of whom had overweight or obesity

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[27] Heart SLE may cause pericarditis (inflammation of the outer lining surrounding the heart), myocarditis (inflammation of the heart muscle), or endocarditis (inflammation of the inner lining of the heart)