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As the in vitro kinase reaction shown, a truncation of Sec24C consisting of only the first 400 residue (C) rather than the remaining portion (N) was phosphorylated by VRK2 (Fig

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Regulatory Status AOD-9604 is not FDA-approved for any medical use and is listed by the FDA as a bulk drug substance that may present safety risks. Clinical development was halted after Phase IIb trials failed to meet efficacy endpoints. Summary AOD-9604 is a synthetic analog of the HGH 177191 fragment developed for fat-metabolism research