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(5) Increased cardiomyocyte contractilityRestoring cardiac contractility and pumping efficiency is a key target of gene therapy, particularly through SERCA2a and its regulatory proteins, which modulate intracellular Ca dynamics to alleviate symptoms in patients with HFrEF and improve long-term outcomes (Fig

DRCT is a polyphenotypic tumor in which distinctive dot-like desmine staining as well as other intermediate filaments can be demonstrated