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Combine this with a genetic variant for an enzyme called diamine oxidase (DAO), the main enzyme responsible for metabolizing ingested histamine, and the result is high histamine which can lead to headaches

In addition to the skin biopsy, patients should request Quantitative Sensory Testing (QST)

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STRUCTURE Glutathione is a tripeptide consisting of three amino acids: glutamate, cysteine, and glycine, hence, described as -l-glutamyl-l-cysteinylglycine [Figure 1].[] INTRACELLULAR DISTRIBUTION OF GLUTATHIONE Glutathione is synthesized from glutamate, cysteine, and glycine in the cytosol