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In addition, the characterized LASSS treatment did not stimulate autolysis of HGF as monitored by SDS-PAGE for degradation of 60-kDa -chain and 90-kDa proform of recombinant HGF incubated with LASSS (at 1:8000) at 25 for 2 h (see supplementary Figure 1b), providing another important basis for the availability of LASSS-HGF
Component trials' stopping rules were defined for single-component administration and do not transfer.
They provide a more holistic picture of the state of cellular metabolism by providing large-scale detection and information on the structural composition and abundance of a broad range of metabolites, although it must be noted it is not possible to detect every metabolite in a system (Amantonico et al., 2010
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