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The STEP 5 trial demonstrated that continued treatment for 104 weeks maintained weight loss, while the STEP 1 extension study showed that discontinuing semaglutide at 68 weeks led to two-thirds of the weight lost being regained within a year
Reserpine is the active ingredient of a herbal tranquillizer from Rauwolfia serpentina discovered by ancient Indian physicians
Mazdutide , a dual GLP-1/glucagon agonist, is in development and shows promising results in early trials, particularly in Asian populations
A year after the study began, the COVID-19 pandemic struck
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