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Unadjusted populations for semaglutide and tirzepatide differ Using Truveta Data, Truveta Research began with a patient population of over 40,000 patients with overweight or obesity initiating either semaglutide or tirzepatide between May 2022 and September 2023

GLP-1 agonists should not directly impair sleep, but if you are taking doses late in the day, residual GI discomfort may disrupt rest

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A history of pancreatitis requires caution but is not an absolute contraindication