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In summary, pDCs have played an unknown harmful role by limiting CD8 T cell responses, and the interaction between pDCs and T cells is not entirely positive, with the boundaries and mechanisms still needing to be confirmed by more research data

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308 The resulting Arg-CysO 2 (H) acts as an N-degron, which is identified by UBR1 and UBR2 for ubiquitylation and subsequent degradation