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This naturally occurring protein has GLP-1 receptor-activating properties, and it is resistant to degradation by the DPP4 enzyme
Thus, even if systemic changes in GLP- 1 levels might not be readily detectable, altered paracrine signaling of GLP-1 could have profound effects on enterochromaffin cells (as mentioned above) (5153), intraepithelial lymphocytes (29) and afferent neurons, in turn impacting intestinal motility, mucosal immune responses and feeding behavior under inflammatory conditions (75)
Furman BL
It is a key substance in detox pathways
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