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Absence of Gclc impairs mitochondrial respiration in FoB Our data above showed that glucose-derived fluxes into the TCA cycle were reduced in GSH-deficient FoB
The structural basis of cellulitethe arrangement of fibrous septae and fat chambersis not directly affected by the metabolic or hormonal changes induced by GLP-1 agonists
A key advancement in addressing these mechanisms is the shift from a neuron-centric to a holistic view that encompasses the critical role of glial cells, a perspective that informs the diverse therapeutic toolkit explored in the following sections
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